|
KMID : 0984720070390050259
|
|
Infection and Chemotherapy
2007 Volume.39 No. 5 p.259 ~ p.262
|
|
|
A Case of Good’s Syndrome
|
|
Song Kyoung-Ho
Kim Hong-Bin
Kim Nam-Joong
Oh Myoung-Don
Choe Kang-Won
Park Kyoung-Un
Kim Kyae-Hyung
Kim Chung-Jong
Jheon Sang-Hoon
|
|
|
Abstract
|
|
|
|
Good’s syndrome is the association of thymoma with immunodeficiency, characterized by hypogammaglobulinemia, B-cell lymphopenia and variably defects in cellular immunity with CD4＋ T-cell lymphopenia and an inverted CD4＋:CD8＋ T-cell ratio. We report a 43-year-old male patient who presented with a 18-month history of productive cough and postnasal drip. One year ago, he underwent the operation for resection of a thymoma. Despite of appropriate management, sinusitis relapsed multiple times. He was found to have hypogammaglobulinemia with nearly absent B cells(4/μL). The CD4＋ T-cell count was 554/μL with an inverted CD4＋:CD8＋ T-cell ratio of 0.6. His symptoms and signs improved with antibiotic treatment and monthly administration of intravenous immunoglobulin (IVIG, 400 mg/kg).
|
|
|
KEYWORD
|
|
|
Good syndrome, Thymoma, Immunodeficiency, Hypogammaglobulinemia
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|